Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms

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Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms.

Bronchiectasis is a chronic and debilitating lung disease, characterised by irreversible dilatation of the bronchi as consequence of airway injury and remodelling due to recurrent or chronic airway inflammation and infection. The underlying aetiologies include autoimmune diseases, severe infections, genetic abnormalities and acquired disorders. The pathogenesis of bronchiectasis is poorly under...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2008

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00069007